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    Antabuse tablet


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    Find patient medical information for Antabuse Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. zoloft medication side effects Antabuse interferes with the metabolism of alcohol and is used to treat chronic alcoholism. Learn about side effects, interactions and indications. Disulfiram Tablets USP are an aid in the management of selected chronic alcohol patients who want to remain in a state of enforced sobriety so that.

    Normalerweise wird in der Leber der aufgenommene Alkohol über die Zwischenstufe Acetaldehyd zur Essigsäure umgewandelt, ähnlich wie bei der Essigherstellung durch Gärung. In diesen Abbau des Alkohols greift nun das Medikament ein und verhindert den letzten Schritt zur Umwandlung in die Essigsäure durch Blockade des Enzyms Aldehyddehydrogenase. Die Folge ist, dass sich der Acetaldehyd anreichert. Dieses bewirkt das sogenannte Acetaldehydsyndrom, welches darin besteht, dass, sobald Alkohol auch in geringen Dosen eingenommen wird, starke und unangenehme Unverträglichkeitsreaktionen entstehen, wie Hautrötung, Kältegefühl in den Armen und Beinen, Übelkeit, Kopfschmerzen und vor allem Herzrasen und Blutdruckabfall bis hin zum Herz-Kreislauf-Schock. Hierdurch kann bei gefährdeten Personen sogar Herzenge, Angina pectoris, und ein Herzinfarkt ausgelöst werden. Entsprechende Arzneimittel werden als Tabletten verabreicht. Es kann auch als Depotpräparat unter die Haut implantiert werden. Da die angesprochenen Unverträglichkeitsreaktionen bei Einnahme größerer Alkoholmengen sogar tödlich sein können (Acetaldehyd ist giftig), werden disulfiramhaltige Präparate nur noch selten und bei solchen Patienten angewandt, bei denen von guter Mitarbeit bei der Behandlung ausgegangen werden kann. Diverse Antibiotika, einige Antidiabetika und weitere Medikamente sowie das Pilzgift Coprin haben in Kombination mit Alkohol die gleiche Wirkung wie Disulfiram (siehe Acetaldehydsyndrom). A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome).

    Antabuse tablet

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  6. Antabuse disulfiram is used for treating chronic alcoholism. If you can't swallow the Antabuse tablets, you can crush them and mix with.

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