I know I had never heard of it until my rheumatologist said that is what I have...along w/osteoarthritis and fibromyalgia. My blood tests are negative for RF but my CRP test was above normal. Ai Yi Yi Plaquenil reduces inflammation in many Rheumatic disorders, the mode of action is pretty complicated though so I shan't bore you with all the details, but basically it prevents your dendritic cells (these are messengers for your immune system, if you will) from interacting with your T-Cells (a special type of white blood cell which through a convoluted and boring process, causes inflammation when an infection is found, and these basically malfunction with inflammatory disorders). So, he started me on 400 mg of Plaquenil a day and he just upped it to 600 mg a day. As I said previously, my Rheumatologist now says it is inflammatory osteoarthrits. Why am I taking Plaquenil, which does help tremedously BTW, if I don't have RA or Lupus. This "dendritic deactivation" (I made that phrase up) helps reduce your immune system being silly and inflaming your joints. Can plaquenil be used for ulcerative colitis Chloroquine and early pregnancy Sep 05, 2017 Rheumatoid arthritis nodules are small, often round bumps caused by swelling. Osteoarthritis nodes are caused by malformations in the bone caused by wear-and-tear. The two most common forms of arthritis can cause different types of arthritis nodules. Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Joint pain is a very common complaint in lupus and may lead to difficulty with one’s usual daily activities. A rheumatologist will try to determine the origin of pain, whether it is in the joint lining which is true arthritis, the soft tissues around the joint due to problems with tendons or ligaments, or the bones. My sister was dx'd with Inflammatory Arthritis and Plaquenil sent her into remission some years ago now. I also take meds for high bp, asthma and high cholesterol. Osteoarthritis joint nodules hydroxychloroquine Joint Pain Johns Hopkins Sjögren’s Center, Hydroxychloroquine Plaquenil Chloroquine phosphate anemonesPlaquenil uses and side effects Mar 02, 2013 Osteoarthritis OA is the most common type of arthritis, causing significant joint pain and disability. It is already a major cause of healthcare expenditure and its incidence will further increase with the ageing population. Current treatments for OA have major limitations and new analgesic treatments are needed. Hydroxychloroquine effectiveness in reducing symptoms of hand.. Is Lupus Causing Your Joint Pain or Is It Really Arthritis?. What are RA Nodules and How are they Treated?. If you’re taking hydroxychloroquine for your hand osteoarthritis OA and expecting relief from the painful symptoms of the disease, you may want to hold it — figuratively speaking. Although the quinoline, which was originally approved as a treatment for malaria, has been used “off-label” for decades in the management. Hydroxychloroquine Plaquenil is a drug that is classified as an anti-malarial drug. Plaquenil is prescribed for the treatment or prevention of malaria. It is also prescribed for the treatment of rheumatoid arthritis, lupus, and the side effects of lupus such as hair loss, joint pain, and more. Hydroxychloroquine is an antimalarial drug which is relatively safe and well-tolerated agent for the treatment of rheumatoid arthritis. Chloroquine is another antimalarial agent that is also sometimes used.