In Sjögren’s, Plaquenil is used to treat many symptoms of Sjögren’s including fatigue, joint symptoms of arthritis and arthralgias (joint pain), dry mouth and dry eyes. Similar to its use in systemic lupus erythematosus, many clinicians feel that it is useful in reducing general Sjögren’s “disease activity.” One of the reasons that physicians feel comfortable in prescribing Plaquenil is its low risk to benefit ratio. Chloroquine malaria medication Plaquenil for cancer Difference between hydroxychloroquine Chloroquine p62 Plaquenil hydroxychloroquine is an effective medication for autoimmune conditions and malaria that comes with less side effects than other DMARDs. Effectively prevents and treats malaria, and treats a certain type of intestinal infection but can cause serious side effects in certain people. Plaquenil is a drug used to treat Rheumatoid Arthritis and Systemic Lupus Erythematosis. It is a very good drug and gives many patients significant relief from their symptoms. Plaquenil related eye complications are not common. Plaquenil can produce pigment changes in the macula of the retina. Plaquenil, widely used to treat lupus, rheumatoid arthritis and other inflammatory and dermatologic conditions, is very effective, and “the risk of toxicity in the first five years for someone without special risk factors is very low,” Dr. Marmor said. However, risk increases with duration of use. As with any medication, allergic reactions including skin rashes and non-allergic reactions can occur. This means that the side effects of Plaquenil are mild and infrequent compared with its potential benefits. Plaquenil side effects from the n eyes Plaquenil and Trazodone hydrochloride drug interactions., Conditions Plaquenil-related Eye Problems Eugene Eye Care Chloroquine and proguanil boots priceAutophagic flux assay chloroquine Some side effects of hydroxychloroquine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Hydroxychloroquine Side Effects Common, Severe, Long Term.. Rx Side Effects New Plaquenil Guidelines and More.. Common Side Effects of Plaquenil. Find patient medical information for Hydroxychloroquine Oral on WebMD including its uses, side effects and safety, interactions, pictures, warnings and user ratings. That said, my doctor had originally prescribed for me to take 100mg/day for one week and then increase to 200mg/day. When I increased to 200mg/day, I had strange side effects that caused me to go back to 100/day. Strange leg cramping, restless leg, nausea and anxiety. In a nutshell, at 200mg/day the side effects outweighed the benefits. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember.