It may have both an anti-spirochaete activity and an anti-inflammatory activity, similar to the treatment of rheumatoid arthritis. And caution is required if patients have certain heart conditions, diabetes, psoriasis etc. Plaquenil pain relief Hydroxychloroquine ocular side effects It does not appear to be safe during pregnancy. Hydroxychloroquine is in the antimalarial and 4-aminoquinoline families of medication. Hydroxychloroquine was approved for medical use in the United States in 1955. Pregnancy It is not necessary to withdraw an antimalarial drug during pregnancy if the rheumatic disease is well controlled; however, the manufacturer of hydroxychloroquine advises avoiding use. Hydroxychloroquine is a quinoline medicine used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. The most serious adverse effects affect the eye, with dose-related retinopathy as a concern even after hydroxychloroquine use is discontinued. The most common adverse effects are a mild nausea and occasional stomach cramps with mild diarrhea. Hydroxychloroquine sulfate pregnancy Hydroxychloroquine Use During Pregnancy, HYDROXYCHLOROQUINE SULFATE Drug BNF content published by NICE Plaquenil and ibdBuy aralen medication Hydroxychloroquine is usually considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known. Talk to your healthcare provider about the risks and benefits of using hydroxychloroquine during pregnancy see Plaquenil and Pregnancy for more information. Precautions and Warnings With Hydroxychloroquine. Hydroxychloroquine Uses, Dosage & Side Effects -. Plaquenil hydroxychloroquine sulfate dosing, indications.. Hydroxychloroquine is recommended as an alternative treatment of pregnant women for uncomplicated malaria in chloroquine-sensitive regions refer to current guidelines CDC 2011. Hydroxychloroquine sulfate tablets, USP are also indicated for the treatment of discoid and systemic lupus erythematosus, and rheumatoid arthritis. CONTRAINDICATIONS Use of this drug is contraindicated 1 in the presence of retinal or visual field changes attributable to any 4-aminoquinoline compound, 2 in patients with known hypersensitivity to 4-aminoquinoline compounds, and 3 for long-term therapy in children. Availability. 200 mg tablets. Actions. Derivative closely related to chloroquine. Antimalarial activity is believed to be based on ability to form complexes with DNA of parasite, thereby inhibiting replication and transcription to RNA and DNA synthesis of the parasite.