Malaria parasites can enter the body through these mosquito bites, and then live in body tissues such as red blood cells or the liver. This medication is used to kill the malaria parasites living inside red blood cells. Typical plaquenil maculopathy oct How to wean from plaquenil What lupus symptoms does plaquenil treat Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Non-chloroquine-resistant. 1 g 600 mg base PO, THEN. 500 mg 300 mg base PO 6-8 hours later, THEN. 500 mg 300 mg base PO at 24 hours & 48 hours after initial dose. Both drugs may be needed for a complete cure and to prevent the return of infection (relapse). In some cases, you may need to take a different medication (such as primaquine) to kill the malaria parasites living in other body tissues. Chloroquine contraindications Chloroquine DermNet NZ, Hydroxychloroquine Side Effects, Dosage, Uses, and More Plaquenil safer than fluoroquinolones WebMD provides common contraindications for Hydroxychloroquine Oral. Find out what health conditions may be a health risk when taken with Hydroxychloroquine Oral Contraindications for Hydroxychloroquine Oral. Aralen, Chloroquine phosphate chloroquine dosing.. CDC - Malaria - Travelers - Choosing a Drug to Prevent Malaria. Chloroquine phosphate is a 4-aminoquinoline compound for oral administration. Chloroquine is an antimalarial and amoebicidal drug. The drug possesses antimalarial actions and exerts a beneficial effect in lupus erythematosus chronic discoid or systemic and acute or chronic rheumatoid arthritis. The precise mechanism of action is not known. Most malaria-endemic areas have high rates of chloroquine resistance. Per the CDC, chloroquine-sensitive areas include Central America west of the Panama Canal, Haiti, the Dominican Republic, and most of the Middle East. See CDC malaria information by country for details Contraindications. Use of Chloroquine phosphate tablets for indications other than acute malaria is contraindicated in the presence of retinal or visual field changes of any etiology. Use of Chloroquine phosphate tablets is contraindicated in patients with known hypersensitivity to 4-aminoquinoline compounds.