It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes, which transmit the parasites that cause the infection, usually in tropical and subtropical parts of the world. Plaquenil dosing mouse Hydroxychloroquine for travel Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Your doctor may prescribe a mild medication first, such as hydroxychloroquine, sold as Plaquenil ®. This medication was originally formulated to prevent and treat malaria, but is now also classified as a disease-modifying antirheumatic drug, or DMARD, which means it treats the underlying disease rather than its symptoms. WebMD explains the causes, symptoms, and treatment of Sjogren's syndrome, a condition in which your eyes, mouth, and other parts of your body get dried out. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. Plaquenil is used to treat other types of infections too. Plaquenil to treat mouth disease Ask the Expert Plaquenil and Sjögren’s, Medications for Sjogren’s Syndrome NYU Langone Health Plaquenil retinopathy visual field Plaquenil is used to treat other types of infections too. For example, it may be combined with an antibiotic to treat chronic Q-fever, which humans usually catch from farm animals or raw milk. The drug may be used to treat a type of blood disease called porphyria cutanea tarda. Plaquenil Hydroxychloroquine - Side Effects, Dosage.. Sjogren's Syndrome Symptoms, Causes, Diagnosis, Treatment. Dealing with Lupus Mouth Sores Causes, Treatment, and Prevention. After these drugs were abandoned for the treatment of malaria, more study was done, and they were found to be effective for discoid lupus, subacute cutaneous lupus, dermatomyositis, rheumatoid arthritis, and psoriatic arthritis. Plaquenil has a better safety profile than chloroquine and is most commonly used today. Preventive treatment of vivax malaria; increased calcium in the blood from sarcoidosis; joint inflammatory disease in children and young adults; skin allergy to sunlight Treatment. Lichen planus on the skin often clears up on its own in months to years. If the disease affects your mucous membranes, it tends to be more resistant to treatment and prone to recur. Whatever treatment you use, you'll need to visit your doctor for follow-up appointments about once a year.