It does not work against certain types of malaria (chloroquine-resistant). The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Chloroquine phosphate indications Plaquenil for pmle How to stop taking plaquenil rheumatoid arthritis Signs that plaquenil is eye damage It can reduce skin problems in lupus and prevent swelling/pain in arthritis, though it is not known exactly how the drug works. OTHER This section contains uses of this drug that are not listed in the approved professional labeling for the drug, but may be prescribed by your health care professional. SIDE EFFECTS. The following adverse reactions have been identified during post-approval use of PLAQUENIL or other 4-aminoqunoline compounds. Because these reactions are reported voluntarily from a population of uncertain size, it is not always possible to reliably estimate their frequency or establish a causal relationship to drug exposure. Plaquenil can cause edema in the feet and legs. One of the warnings says to contact your doctor if you develop swelling/edema in the feet and legs. I had a medication cause me to retain fluid and I gained 6.5 pounds in 2 days. All of it was in my legs and feet. This medication is also used, usually with other medications, to treat certain auto-immune diseases (lupus, rheumatoid arthritis) when other medications have not worked or cannot be used. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. Can plaquenil cause edema How to Avoid Having Heavy Legs & Swelling of Ankles Healthfully, Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses Chloroquine mechanism of action iodineOcular effects of hydroxychloroquineWithdrawal from hydroxychloroquineKeyhole hydroxychloroquineAralen chloroquine phosphate Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Plaquenil. Please tell me about your swollen ankles/calves.there.. Rx Side Effects New Plaquenil Guidelines and More.. Plaquenil and SLE Plaquenil Itchy feet and palms alternatives to plaquenil plaquenil as lyme treatment Swollen feet, nausea, fever Swelling of hands,feet, and ankles. will not go away! Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. Heavy legs and edema in the ankles occur due to vascular insufficiency. Monitor your diet and eliminate salt when possible. This leads to swelling in the ankles and high-blood pressure. Keeping your legs above your heart helps maintain the flow of venous blood. Heavy legs and edema may be secondary to another illness such as diabetes.