Quinacrine hydrochloride also has the 4-amino quinoline radical but has, in addition, a benzene ring; it is classified as an acridine compound. The 4-amino quinoline radical is present in all antimalarial compounds shown to be effective in the treatment of lupus erythematosus (LE) (Figure). Effects of plaquenil on teeth Plaquenil sun allergy Plaquenil and pepto bismol Plaquenil is an extremely safe medication, with few side effects gastrointestinal complaints the first 2-3 weeks are the most common. It has numerous benefits on lupus and in general tends to lower cholesterol for instance. It is interesting that you were first prescribed mepacrine/quinacrine instead of Plaquenil. To evaluate the efficacy of hydroxychloroquine HCQ and quinacrine Qn association, at two different dosages, in treatment of lupus skin lesions not responding to HCQ alone. Quinacrine in the treatment of Cutaneous Lupus Erythematosus Practical Aspects and a Case Series 57 A quinacrine preparation in combination with another antimalarial agent chloroquine or hydroxychloroquine was subsequently marketed for the treatment of discoid lupus. 2 At the end of the 1970s, however, this preparation, along with many other combination therapies, was withdrawn from the market by the US Food and Drug Administration. Its superiority over quinine was established during World War II, when it became the official drug for the treatment of malaria. Quinacrine was introduced for malaria therapy in 1930. Quinacrine and hydroxychloroquine lupus profundus Mepacrine in Recalcitrant Cutaneous Lupus Erythematosus., Treatment of lupus skin involvement with quinacrine and hydroxychloroquine Decoration ideas for posters about chloroquineHydrocloroquine plaquenilChloroquine phosphate molecular weightSaltwater fish chloroquine compatibilityWhat tier is hydroxychloroquine Abstract. Background Although the benefit of antimalarials in the treatment of cutaneous LE is well established, the effect of combined hydroxychloroquine and quinacrine treatment in systemic lupus erythematosus with major organ involvement remains underappreciated. Patients Six active SLE patients SLEDAI score 5 points. The benefit of combining hydroxychloroquine with quinacrine in the.. Quinacrine in the Treatment of Cutaneous Lupus Erythematosus.. Discoid Lupus Erythematosus Medication Antimalarial agents.. Today’s AMs are hydroxychloroquine Plaquenil®, chloroquine Aralen®, and quinacrine Atabrine®. Quinacrine is no longer marketed in the U. S.; it can be dispensed by a compounding pharmacy, although insurance companies may not pay for it. The antimalarial quinine was first used to treat cutaneous lupus in 1834. Hydroxychloroquine Plaquenil Chloroquine Aralen Quinacrine Atabrine What are anti-malarial drugs, and why are they used to treat lupus? Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. Hydroxychloroquine and chloroquine are antimalarials used as first-line treatment of cutaneous lupus. Quinacrine is not often employed by Spanish physicians due to a lack of information about its use and the fact that it is not marketed in Spain. It is effective in monotherapy or in combination therapy with other antimalarials.