One such commonly used medication for dermatologic and rheumatologic inflammatory conditions is hydroxychloroquine (Plaquenil), a chloroquine derivative. It is used to treat many diseases including malaria, rheumatoid arthritis and systemic lupus erythematosus. Plaquenil vs rituximab rituxan Drugs administered with chloroquine Plaquenil ra forum I had been taking plaquenil since April for my lupus and sjogrens. It was working really well and just recently my rheumy told that I was in remission. I felt great. Then I had an allergic reaction to the plaquenil - a rash all over my body, neck, arms and legs. I stopped taking it 1 week ago. Most side effects will go away when your body gets used to the medicine. Tell your doctor if you have these side effects. A lower dose may stop them. Do not lower the dose on your own. Plaquenil stays in your body for about 3 months. If you must stop it, it will take a while for the side effects to go away. Side Effects Nausea, stomach cramps, loss of appetite, diarrhea, dizziness, or headache may occur. If any of these effects persist or worsen, notify your doctor or pharmacist promptly. Remember. It is imperative that patients and physicians are aware of and watch for this drug’s ocular side effects. Retinal toxicity from hydroxychloroquine is rare, but even if the medication is discontinued, vision loss may be irreversible and may continue to progress. Swelling after stopping plaquenil Ask the Expert Plaquenil and Sjögren’s, Lupus Medicines Hydroxychloroquine - Brigham and Women's. Plaquenil with valium Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. Let me tell you what weaning down from Plaquenil is like.. Plaquenil Oral Uses, Side Effects, Interactions.. Myositis Symptoms and Causes - WebMD. Take it once weekly while in the area, and continue taking it for 4 to 8 weeks after leaving the area or as directed by your doctor. To treat malaria, follow your doctor's lupus or rheumatoid arthritis, take this medication by mouth, usually once or twice daily or as directed. As some of you know I started on Plaquenil 6 weeks ago. After two weeks I stopped it because of liver pain, and we found out I had raised liver enzymes. I stayed off it for two weeks until I could contact my rheumatologist who was on holiday My rheumatologist did not think think the Plaquenil w. Aug 29, 2014 Early detection of the maculopathy is of critical importance to discontinue Plaquenil in order to stop or slow retinal damage. Unfortunately, clinically evident early structural changes can be subtle and usually preceded by abnormalities in functional tests such as visual field examination.