Plaquenil is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. Chloroquine cell toxicity Chloroquine eye drops Can a patient on plaquenil get the varicella vaccine Hydroxychloroquine dosage for sjogren's syndrome Jan 01, 2020 Weight based dosage in adults and pediatric patients 13 mg/kg 10 mg/kg base, not to exceed 800 mg 620 mg base followed by 6.5 mg/kg 5 mg/kg base, not to exceed 400 mg 310 mg base, at 6 hours, 24 hours and 48 hours after the initial dose. Plaquenil film-coated tablets cannot be divided, therefore they should not be used to treat. Standard dosing At first, 800 milligrams mg 4 tablets taken as a single dose. Then, 400 mg taken 6 hours, 24 hours, and 48 hours after the first dose. Weight-based dosing Dose is based on body weight and must be determined by your doctor. At first, 13 milligram mg per kilogram kg of body weight taken as a single dose. Let's dive in. Melton & Thomas describe the typical safe Plaquenil dosage this way The usual dosage is two 200mg tablets per day. This is generally a "safe" dose for patients having a lean body weight of at least 135 lbs. The generally-regarded safe dosage is 6.5mg/kg/qd, thus the 135 lb. safety threshold. Plaquenil is also an antirheumatic medicine and is used to treat symptoms of rheumatoid arthritis and discoid or systemic lupus erythematosus. This medicine is not effective against all strains of malaria. Plaquenil dosing by weight Plaquenil Risk Calculators, Hydroxychloroquine Oral Route Proper Use - Mayo Clinic Cornea verticillata hydroxychloroquine Hydroxychloroquine may inhibit P-glycoprotein P-gp. Digoxin is a substrate for P-gp transport. For patients on a stable digoxin regimen and initiating hydroxychloroquine, no initial dose adjustment of either drug has been advised; however, serum digoxin concentrations should be monitored and used for digoxin dose titration as clinically. Plaquenil hydroxychloroquine sulfate dose, indications.. Daily Plaquenil Dosage - Crunching Numbers —. Protecting your eyesight when taking Plaquenil Lupus.. Background/Purpose Hydroxychloroquine HCQ is a widely-used medication in many rheumatologic conditions. The most worrisome toxicity is irreversible damage to retinal pigment epithelium which can lead to blindness. The most recent 2016 guidelines from the American Academy of Ophthalmology AAO recommend the dose of HCQ ≤5 mg/kg real body weight to minimize toxicity1. According to these Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Dosage is based on body weight. The typical. Plaquenil caused some weight loss for me when I was on a higher dose. Now that I am on 200 mg. per day, I don't notice that anymore. Prednisone, on the other hand, has caused both a gain/loss, depending on the dosage. I noticed a six pound gain with Benlysta happened pretty quickly. That might change now that I am off the Benlysta.