I did stop it for 2 weeks early in the treatment due to having to take a coupld other drugs that seemed to give me side effects. I just quit the plaquenil to give my liver a rest at that time. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. Chloroquine usmle Chloroquine sensitive malaria areas Chloroquine p falciprum I have had to stop my plaquenil and aside from the fatigue and joint pain that I knew I would have, I also now have a sunburned look on my face when I go out in the sun and itching skin, almost like a hive type rash on my back. Has anyone else ever had this after stopping the plaquenil. Plaquenil isn a antiparasitic drug with anti-inflammatory affect. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I took plaquenil on and off over a period of yrs. Stopped talikg fist time because it reacts with the sun. Got over heated one day and head felt like it was on fire. It was also causing hair loss. My doctor took me off it at the time. Because of A problem I have taking arthritis meds he suggested I try it again. Over the years on this site we have had quite a few people post that they didn't think that the plaquenil was working so they would stop taking it. I have done a lot of research on this drug and haven't run into anybody who has complained of the withdrawal effect. Can plaquenil ever be stopped abruptly PLAQUENIL Side Effects, Reviews by Patients -, Let me tell you what weaning down from Plaquenil is like. Plaquenil eye damage reversibleSkin cancer risk f plaquenilPlaquenil black box warning May 07, 2012 Saturday was a week since I stopped taking Plaquenil, aka Hydroxychloroquine, per my doctor's instructions, and I think I am going through some form of withdrawal. I took the drug as a treatment for sarcoidosis and one of the side effects is a reduction in white blood cells, which is what has happened to me. Plaquenil Withdrawal – Life As An Anomaly. Does plaquenil elevate your liver enzymes? ProHealth.. Hydroxychloroquine Side Effects, Dosage, Uses, and More. I was prescribed plaquenil for Sjogrens about 5 years ago by my rheumatogist. I too was afraid of the side effects and didn't realize that the disease would worsen, so I just didn't take the plaquenil. Two years later I began having pericarditis attacks and wound up in the hospital. My biggest concern is the Sarcoidosis and how it will feel after a couple of days off the Plaquenil. I hope it isn't to bad. Anyway, I will let you guys know how it goes. Though Plaquenil is generally regarded as safe during pregnancy, it is recommended that effective birth control is used throughout the course of Plaquenil treatment and for up to six months after treatment is stopped.