These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Plaquenil for pregnancy loss Plaquenil wrong medication Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention. Check with your doctor immediately if any of the following side effects occur Incidence not known. Blistering, peeling, loosening of the skin blurred vision or other vision changes chest discomfort, pain, or tightness cough or hoarseness dark urine decreased urination defective color vision diarrhea difficulty breathing Apr 10, 2019 Common Plaquenil side effects may include headache, dizziness, ringing in your ears; nausea, vomiting, stomach pain; loss of appetite, weight loss; mood changes, feeling nervous or irritable; skin rash or itching; or. hair loss. If you notice any other effects, check with your healthcare professional. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Other side effects not listed may also occur in some patients. Adverse effects of long term use of plaquenil Protecting your eyesight when taking Plaquenil Lupus., Hydroxychloroquine Oral Route Side Effects - Mayo Clinic Concurrent administration of chloroquine Avoid alcoholic beverages because they may increase your risk of liver problems while you are taking this drug. Caution is advised when using this drug in children because they may be more sensitive to the side effects of the drug. This medication is not recommended for long-term use in children. HYDROXYCHLOROQUINE - ORAL Plaquenil side effects, medical.. Plaquenil Uses, Dosage & Side Effects -. Plaquenil - Side Effects, Uses, Dosage, Overdose, Pregnancy.. Plaquenil is the brand name for the prescription drug hydroxychloroquine. It's used to treat and prevent malaria infection, and to reduce symptoms and progression of autoimmune diseases such as lupus, rheumatoid arthritis, and others. Malaria is spread by mosquitoes. Methotrexate vs plaquenil side effects long term and short term I was recently diagnosed with an autoimmune disease that mainly fuses my joints together, but causes severe pain and fatigue. The only problem is the Plaquenil causes severe headaches that interfer with my daily activities also. Potential side effects of anti-malarial drugs include Skin rashes and pigment change. Atabrine, specifically, can cause yellow pigmentation of skin. Sometimes Plaquenil can also deposit in the tissues of the body and cause the skin to take on a greenish tone. Dry skin. Loss of appetite. Abdominal bloating. Upset stomach.