Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. AU TGA pregnancy category D: Drugs which have caused, are suspected to have caused or may be expected to cause, an increased incidence of human fetal malformations or irreversible damage. These drugs may also have adverse pharmacological effects. Potential adverse effect with hydroxychloroquine Oct testing in plaquenil macular toxicity Hydroxychloroquine Plaquenil is considered a disease-modifying anti-rheumatic drug DMARD. It can decrease the pain and swelling of arthritis. It may prevent joint damage and reduce the risk of long-term disability. Hydroxychloroquine is in a class of medications that was first used to prevent and treat malaria. Hydroxychloroquine Pregnancy Warnings Animal studies have revealed evidence of fetal harm. Use of chloroquine and other 4-aminoquinolines in high doses and for prolonged durations has been associated with neurological disturbances and interference with hearing, balance, and vision in the fetus. Plaquenil is sold in 200mg tablets. The recommended adult dosage for a person with lupus is 200 to 400 mg daily. It can be taken in two doses or at one time. Doses above 400 mg/day are not recommended. US FDA pregnancy category Not Assigned: The US FDA has amended the pregnancy labeling rule for prescription drug products to require labeling that includes a summary of risk, a discussion of the data supporting that summary, and relevant information to help health care providers make prescribing decisions and counsel women about the use of drugs during pregnancy. Accompanying texts should be consulted for further details. Plaquenil pregnancy lupus Hydroxychloroquine MotherToBaby, Hydroxychloroquine Use During Pregnancy Plaquenil et piluleChloroquine phosphate tablet ip 250 mg Pregnancy constitutes a challenge in patients with systemic lupus erythematosus SLE. Apart from disease flares during pregnancy, SLE patients have an increased risk of intrauterine growth restriction OR 2.6, preeclampsia OR 3.0, and preterm birth OR 2.4 compared to the healthy population 1. Hydroxychloroquine Use in Lupus Patients during Pregnancy Is.. Plaquenil Hydroxychloroquine for Lupus - LupusCorner. Lupus and Pregnancy - Kaleidoscope Fighting Lupus. Hydroxychloroquine Plaquenil, chloroquine Aralen, and quinacrine Atabrine are medications that were originally used to prevent or treat malaria. However, during World War II it was also found that these medications were effective in treating the symptoms of lupus. Hydroxychloroquine Plaquenil is used to treat malaria, lupus, and rheumatoid arthritis. Learn about side effects, warnings, dosage, and more. Plaquenil ® hydroxychloroquine sulfate is a prescription anti-malarial medication that is also used to treat lupus and rheumatoid arthritis. In many cases, the benefits of using Plaquenil for malaria prevention or treatment in pregnant women outweigh the risks.