Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take hydroxychloroquine with all of your drugs and health problems. Statistics plaquenil maculopathy Biaxin bactrim plaquenil for bartonella Plaquenil and weight loss Hydroxychloroquine is used to treat or prevent malaria, a disease caused by parasites that enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia. This medicine is not effective against all strains of malaria. Plaquenil side effects. Get emergency medical help if you have signs of an allergic reaction to Plaquenil hives; difficulty breathing; swelling of your face, lips, tongue, or throat. Taking Plaquenil long-term or at high doses may cause irreversible damage to the retina of your eye. The main symptom of the plaque on the tongue is the change of color from gently pink to grayish sometimes to dark gray. In severe pathologies, the usual color of the tongue through the plaque is not translucent. Gray coating on the tongue can be accompanied by the appearance of an unpleasant odor. For all uses of hydroxychloroquine: WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. Do not start, stop, or change the dose of any drug without checking with your doctor. Plaquenil tongue Plaquenil Side Effects - GoodRx, Plaquenil Uses, Dosage & Side Effects - Hydroxychloroquine sarcoidosisChloroquine mechanism in the bodyPlaquenil and radiation therapy toxiciy Plaquenil; Descriptions. Hydroxychloroquine is used to treat malaria. It is also used to prevent malaria infection in areas or regions where it is known that other medicines eg, chloroquine may not work. Hydroxychloroquine Oral Route Description and Brand Names.. Gray coating on the tongue Causes and treatment of gray.. Hydroxychloroquine Uses, Dosage & Side Effects -. Hi Amy. I don't take cytoxan, but I do have all the CNS problems you mentioned. I recently had a full neuropsych exam MRI, EEG and everything was normal. I've been having periodic loss of sensation tongue is really weird, tremors, loss of balance for a few years now. I personally think anyone who has CNS problems should get a thorough exam. View detailed reports from patients taking plaquenil who experienced tongue disorder. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. The risk may also be higher with some doses of hydroxychloroquine, if you use hydroxychloroquine for longer than 5 years, or if you take certain other drugs like tamoxifen. Call your doctor right away if you have any eyesight changes like blurred or foggy eyesight, trouble focusing or reading, or trouble seeing in dim light.