Chloroquine dosing for lupus retina

Discussion in 'Canadian Pharmacy Online' started by ztop, 24-Feb-2020.

  1. anna_shug Well-Known Member

    Chloroquine dosing for lupus retina


    Pattern of Retinopathy: Although the locus of toxic damage is parafoveal in many eyes, Asian patients often show an extramacular pattern of damage. Dose: We recommend a maximum daily HCQ use of 5.0 mg/kg real weight, which correlates better with risk than ideal weight.

    Hydroxychloroquine dose Do i need monthly blood test while taking hydroxychloroquine

    Recommendations on Screening for Chloroquine and Hydroxychloroquine Retinopathy Retinal toxicity from chloroquine CQ and its analogue, hydroxychloroquine HCQ, has been recognized for many years. Chloroquine toxicity remains a problem in many parts of the world, but is seen less frequently in the United States where the drug largely has been replaced by HCQ. Chloroquine retinopathy, is a form of toxic retinopathy damage of the retina caused by the drugs chloroquine or hydroxychloroquine, which are sometimes used in the treatment of autoimmune disorders such as rheumatoid arthritis and systemic lupus erythematosus. This eye toxicity limits long-term use of the drugs. Hydroxychloroquine is generally prescribed at a daily dose of 6.5 milligrams or less per kilogram of body weight. Using this formula, the dosage for a 150-pound person would be 443 mg/day, as one kilogram equals 2.2 pounds. Because HCQ is formulated as a 200 mg tablet, many people taking it for lupus will take two pills per day.

    Risk of Toxicity: The risk of toxicity is dependent on daily dose and duration of use. There are no similar demographic data for CQ, but dose comparisons in older literature suggest using 2.3 mg/kg real weight.

    Chloroquine dosing for lupus retina

    Spotlight Case Chloroquine - The American Society of Retina., Chloroquine retinopathy - Wikipedia

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  5. Chloroquine has a particularly high affinity for melanin -containing cells and hence there are very high levels of chloroquine in the skin mainly, the epidermis and retina. Chloroquine has a long half-life, which can vary between 74 hours and 50 days, depending on the cumulative dose.

    • Chloroquine DermNet NZ.
    • Drug spotlight on hydroxychloroquine Lupus Foundation of..
    • Chloroquine Retinopathy - an overview ScienceDirect Topics.

    The dose for treating children is 10 mg/kg for the first dose then 5 mg/kg daily for 2 days, starting 6 hours after the first dose. The dose for treating intestinal amebiasis is 1 g daily for two days, followed by 500 mg daily for at least two to three weeks. Chloroquine usually is combined with an effective intestinal amebicide. The maximum dose of Plaquenil is 6.5 mg/kg of ideal body weight per day, regardless of whether a person is overweight, underweight, or normal weight. One kilogram kg equals 2.2 pounds. Women with lupus who are OVER their ideal body weight should go by these dosing rules 5’ 7” or higher - up to 400 mg Plaquenil daily Jan 05, 2020 Hydroxychloroquine Plaquenil and chloroquine cause ocular toxicity to various parts of the eye such as the cornea, ciliary body, and retina. Chloroquine can also induce cataract formation; however, no reports of hydroxychloroquine and cataract have been reported 1.

     
  6. goldip Well-Known Member

    Applies to hydroxychloroquine: oral tablet Along with its needed effects, hydroxychloroquine (the active ingredient contained in Plaquenil) may cause some unwanted effects. Does plaquenil hydroxychloroquine for sle lupus make you. Lupus Symptoms In Women - How To Know If You Have Lupus Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses
     
  7. VooDooworks XenForo Moderator

    I used Plaquenil years ago for extreme muscle and joint issues and it seemed to work fine. Plaquenil What You Need to Know - Kaleidoscope Fighting Lupus Plaquenil but no diagnosis Lupus Forums at The Lupus Site Plaquenil Hydroxychloroquine - Other Prescriptions.
     
  8. AlexTime User

    Hydroxychloroquine MedlinePlus Drug Information Hydroxychloroquine is in a class of drugs called antimalarials. It is used to prevent and treat acute attacks of malaria. It is also used to treat discoid or systemic lupus erythematosus and rheumatoid arthritis in patients whose symptoms have not improved with other treatments.

    Prescribing Framework for Hydroxychloroquine in Rheumatic.
     
  9. Poll555 Guest

    Hydroxychloroquine/QT Prolonging Agents Interactions Hydroxychloroquine/QT Prolonging Agents Interactions. This information is generalized and not intended as specific medical advice. Consult your healthcare professional before taking or.

    Plaquenil Hydroxychloroquine - Side Effects, Dosage.