Hydroxychloroquine is used to prevent or treat malaria infections caused by mosquito bites. It does not work against certain types of malaria (chloroquine-resistant). Chloroquine drug Hydroxychloroquine and kidney function Allergic and psoriasis-like rashes tend to develop within the first few weeks or months of starting Plaquenil. If Plaquenil helps a serious chronic disease such as lupus, it may be taken for years. Some of these long-term users will develop grayish-blue pigmentation on. Pigmentation associated with long-term use of Plaquenil. their shins and forearms. Plaquenil hydroxychloroquine is considered an older DMARD disease modifying anti-rheumatic drug. Plaquenil was actually first classified as an antimalarial drug, but it is also used to treat certain rheumatic and autoimmune conditions which are unrelated to malaria. Generally, Plaquenil is a treatment option as monotherapy used alone for mild rheumatoid arthritis or as combination. View detailed reports from patients taking plaquenil who experienced muscle spasms. Reports are from official medical reports as well as online extractions from user reviews and forum discussions. Discuss the most recent information with your doctor before traveling to areas where malaria occurs. The United States Center for Disease Control provides updated guidelines and travel recommendations for the prevention and treatment of malaria in different parts of the world. Plaquenil helps spasms Side Effects of Plaquenil Hydroxychloroquine, Warnings, Uses, Taking Plaquenil for Rheumatoid Arthritis Plaquenil and radiation therapyChloroquine phosphate tablets bp 250 mgStopping plaquenil medication Plaquenil hydroxychloroquine sulfate daily for two weeks, then once per week. 5 Quinine is the best-studied drug for nocturnal leg cramps and has been found effective in some studies. Yet quinine is no longer routinely recommended for treatment due to the potential for serious and/or life-threatening side effects. Nighttime Leg Cramps Meds That Hurt, Meds That Help - GoodRx. Hydroxychloroquine Sulfate Muscle Spasms Reports - DrugInformer. Plaquenil Side Effects - GoodRx. Sep 13, 2019 Some of the dosage forms listed on this page may not apply to the brand name Plaquenil. For the Consumer. Applies to hydroxychloroquine oral tablet. Along with its needed effects, hydroxychloroquine the active ingredient contained in Plaquenil may cause some unwanted effects. Although not all of these side effects may occur, if they do occur. Plaquenil can make you completely blind! *Legitimate looking vitamins I take to help remediate it I took Plaquenil for over 13 years and it caused me and 6 in every 1000 patients, new research shows to have toxic maculopathy it caused. *re even if you quit taking the drug, it can continue to damage the eye until blindness occurs. Apr 28, 2009 I've been taking Plaquenil 400 mg for nearly 6 mos. I didn't seem to have any problems whatsoever with it initially, other than very short term and mild cramping/diarrhea. But now I've been dealing with considerable muscle aching and pain/spasm in some new places - or at least places that haven't bothered me in quite awhile.