Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Ocular effects of chloroquine therapy Plaquenil and unexplained bruising Chloroquine phosphate reef central Purpose. To evaluate the role of spectral-domain optical coherence tomography SD-OCT in early detection of Chloroquine maculopathy in rheumatoid arthritis RA patients. iMethods/i. 40 left eyes of 40 female rheumatoid arthritis patients who received treatment chloroquine for more than one year were recruited in the study. Mar 15, 2019 Chloroquine and hydroxychloroquine belong to the quinolone family. They are related drugs with similar clinical indications for use and similar manifestations of retinal toxicity, although their therapeutic and toxic doses differ. CHLOROQUINE AND HYDROXYCHLOROQUINE Chloroquine and its derivative, hydroxychloroquine sulfate, which have been useful in treating malaria and in larger doses, collagen-vascular disease, cause a cumulative dose-related pigmentary retinopathy. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine maculopathy ppt Chloroquine - Wikipedia, Chloroquine and Hydroxychloroquine Toxicity Clinical Presentation Hydroxychloroquine-induced pigmentationRan out of plaquenil Feb 24, 2018 Chloroquine retinopathy 28. Macular Degeneration Stargardt’s Disease 29. Limitations of ERG • Since the ERG measures only the mass response of the retina, isolated lesions like a hole hemorrhage, a small patch of chorioretinitis or localized area of retinal detachment can not be detected by amplitude changes. Electroretinogram erg - LinkedIn SlideShare. Drug induced maculopathy by Dr Jay Chhablani. Chloroquine Retinopathy Is Fluorescein Angiography Necessary.. Oct 25, 2015 Chloroquine 1. Pharmacology IV Topic Anti Malarial Drug Chloroquine 1 2. Contents Classification Pharmacokinetics Biochemistry of plasmodium Mechanism of action of chloroquine Pharmacological actions Adverse effects Uses and contraindications 2 Hydroxychloroquine Maculopathy An Update on Screening and Diagnosis A brief guide for imaging SHIRI SHULMAN, MD. H ydroxychloroquine HCQ; Plaquenil, Sanofi, Bridgewater, NJ is an antimalarial agent that is also commonly used as a treatment for a variety of rheumatologic and dermatologic conditions, such as rheumatoid arthritis and systemic lupus erythematosus. Chloroquine, can be fatal. Medication should be stored in childproof containers out of the reach of infants and children. How long is it safe to use chloroquine? CDC has no limits on the use of chloroquine for the prevention of malaria. When chloroquine. is used at higher doses for many years, a rare eye condition called retinopathy has occurred.