Chloroquine has been extensively used in mass drug administrations, which may have contributed to the emergence and spread of resistance. It is recommended to check if chloroquine is still effective in the region prior to using it. Plaquenil afecta los ojos Plaquenil tylenol interaction Chloroquine diphosphate Catalog No. T0194 CAS 50-63-5 Synonyms Aralen phosphate, Chingamin phosphate Chloroquine is an aminoquinoline antimalarial and also is widely used as an autophagy inhibitor. Product name Chloroquine diphosphate, apoptosis and autophagy inhibitor. Description Antimalarial; apoptosis and autophagy inhibitor. Biological description Antimalarial agent. Inhibits tumor cell growth and metastasis and induces apoptosis in vitro. Chloroquine diphosphate is a 4-aminoquinoline anti-malarial and anti-rheumatoid agent. For example, to modify the dose of resveratrol used for a mouse 22.4 mg/kg to a dose based on the BSA for a rat, multiply 22.4 mg/kg by the K m factor for a mouse and then divide by the K m factor for a rat. The Centers for Disease Control and Prevention recommend against treatment of malaria with chloroquine alone due to more effective combinations. In areas where resistance is present, other antimalarials, such as mefloquine or atovaquone, may be used instead. Chloroquine diphosphate stock Chloroquine diphosphateATM/ATR activatorbuy chloroquine diphosphate., Chloroquine diphosphate CAS 50-63-5 98% purity. - Abcam Buy aralen medicationChloroquine phosphate buy over the counterPlaquenil blurry eyes Sasaki et al 2010 Chloroquine potentiates the anti-cancer effect of 5-fluorouracil on colon cancer cells. BMC Cancer 10 370 PMID 20630104. If you know of a relevant reference for Chloroquine diphosphate, please let us know. Chloroquine diphosphate Supplier CAS 50-63-5 Tocris.. Chloroquine diphosphate Chloroquine Phosphate CAS 50.. Chloroquine diphosphateAntimalarial drugCAS# 50-63-5. Chloroquine binds to heme or FP to form the FP-chloroquine complex; this complex is highly toxic to the cell and disrupts membrane function. Action of the toxic FP-chloroquine and FP results in cell lysis and ultimately parasite cell autodigestion. Selected citations for Chloroquine diphosphate include 2 Citations Showing 1 - 2 Corilagin inhibits breast cancer growth via reactive oxygen species-dependent apoptosis and autophagy. The mechanism of chloroquine diphosphate inducing cells autophagy is arresting cells in G1, up-regulates the expression of p27 and p53 while down-regulates the expression of CDK2 and cyclin D1 3. Apart from anti-malarial, chloroquine diphosphate also has long been reported functioning in cell apoptosis.