Most importantly, you help support continued development of this site. The majority of cases of retinotoxicity have occurred in patients that have had a cumulative dose exceeding 1000g of hydroxychloriquine (Plaquenil). This level is reached in about 7 years with the most common daily dose of Plaquenil, 400 mg/day (200 bid). Plaquenil drug monograph Plaquenil tabs Can plaquenil help osteoarthritis Uses of hydroxychloroquine Mar 17, 2019 1.5 to 15 years 7 mg/kg orally per day added to first course treatment for JDMS if the patient presented with extensive skin rash and needed steroids in high doses Each dose should be taken with a meal or a glass of milk. What other drugs will affect hydroxychloroquine? However, dose is usually not more than 800 mg for the first dose and not more than 400 mg for the next doses. Children—Dose is based on body weight and must be determined by your doctor. At first, 13 mg per kg of body weight taken as a single dose. Then, 6.5 mg per kg of body weight taken 6 hours, 24 hours, and 48 hours after the first dose. A risk factor for Plaquenil hydroxychloroquine retinotoxicity is a daily dose that exceeds 5.0 mg of drug per kg of body weight. The tool on the right simply calculates this threshold based on a patient’s real body weight. It now solely uses real body weight (rather than ideal body weight) based on new recommendations from a 2014 study (1). Disclaimer: This tool is designed to help eye care professionals better understand the risk the of retinotoxicity from hydroxychloroquine. Please note: This calculator was modified in 9/2015. Hydroxychloroquine dose per kg Plaquenil hydroxychloroquine sulfate dosing, indications., What is Hydroxychloroquine? - GoodRx AralenePlaquenil increased heart rateHydroxychloroquine and sulfasalazine combinationPlaquenil skin side effects picturesPlaquenil chinese translation The typical starting dose is 13 mg/kg maximum dose 800 mg. Additional doses of 6.5 mg/kg maximum dose 400 mg should be given at the following times 6 hours after the first dose, 24 hours. Hydroxychloroquine Side Effects, Dosage, Uses, and More. Plaquenil Risk Calculators. Hydroxychloroquine Plaquenil. Kg or more 1 g chloroquine phosphate 600 mg base orally as an initial dose, followed by 500 mg chloroquine phosphate 300 mg base orally after 6 to 8 hours, then 500 mg chloroquine phosphate 300 mg base orally once a day on the next 2 consecutive days Jul 05, 2018 Correspondingly, the median HCQ dose per IBW declined from 6.0 mg/kg to 5.7 mg/kg during the study period, and the median HCQ dose per ABW declined from 4.4 mg/kg to 4.1 mg/kg both p values 0.01 Fig. 1. Dec 30, 2015 SAN FRANCISCO – Hydroxychloroquine Plaquenil dosing based on actual body weight – instead of ideal weight – is appropriate for patients with systemic lupus erythematosus SLE, according to a review of 686 lupus patients at Johns Hopkins University in Baltimore. Most were dosed by actual weight, 6.5 mg/kg up to a maximum of 400 mg/day.